December 10, 2025Infectious Agents and CancerOpen Access

Epstein-Barr virus infection shapes the genetic, transcriptomic, and immune microenvironment landscape of Burkitt lymphoma

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Authors

QXQing XiaoNantong University YZYilei ZhangCentral South University ZCZhongyi ChenHuaqiao University

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Implication

Analysis reveals Epstein-Barr virus influences transcriptomic profiles and prognostic biomarkers in Burkitt lymphoma, suggesting new therapeutic targets.

Key Points

Burkitt lymphoma presents distinct molecular profiles based on Epstein-Barr virus status, impacting prognosis.
Notable prognostic biomarkers identified include SULT1C2P1 and KCNK5 associated with Epstein-Barr virus.
Analysis using transcriptomic and immune profiling elucidates differences in Burkitt lymphoma subtypes.
Findings underscore the significance of Epstein-Barr virus in defining therapeutic approaches for Burkitt lymphoma.

Cite This Study

Xiao et al. (2025) studied this question.

synapsesocial.com/papers/69401b3d2d562116f28f80b7 https://doi.org/10.1186/s13027-025-00720-9

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Implication

Analysis reveals Epstein-Barr virus influences transcriptomic profiles and prognostic biomarkers in Burkitt lymphoma, suggesting new therapeutic targets.

Epstein-Barr virus infection shapes the genetic, transcriptomic, and immune microenvironment landscape of Burkitt lymphoma

Discussion

Member takes

Implication

Key Points

Cite This Study

Epstein-Barr virus infection shapes the genetic, transcriptomic, and immune microenvironment landscape of Burkitt lymphoma

Discussion

Member takes

Implication

Key Points

Cite This Study

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