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December 9, 2025NutrientsOpen Access

The Relationship Between Bioelectrical Impedance Analysis Parameters and Laboratory Biomarkers in an Elderly Polish Cohort: A Cross-Sectional Study

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Authors

ATAnna TomasiewiczMilitary HospitalTTTomasz TargowskiNational Institute of Geriatrics, Rheumatology and RehabilitationSMSebastian MakuchMedical University of Warsaw

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Overview

Cross-sectional study shows sarcopenia and nutritional status linked to phase angle in Polish elderly, suggesting BIA as a useful assessment tool.

Key Points

  • The research aimed to evaluate the relationship between bioelectrical impedance analysis parameters and laboratory biomarkers in elderly Polish adults.
  • Conducted a cross-sectional study with 126 elderly participants (106 women, 20 men) aged 72.4 years on average.
  • Utilized multi-frequency segmental bioelectrical impedance analysis to measure fat-free mass, skeletal muscle mass, and phase angle.
  • Assessed nutritional status with the Mini Nutritional Assessment and analyzed venous blood samples for biomarkers.
  • MNA-defined malnutrition risk was associated with lower muscle mass and phase angle, highlighting sarcopenia as a concern.
  • Adiposity correlated strongly with leptin and CRP, while hematological parameters were linked to lean mass.
  • Canonical analysis identified two physiological axes: an 'adipo-hormonal' axis linking leptin to fat mass and a 'metabolic-cellular integrity' axis relating zinc and iron status to phase angle.

Cite This Study

Tomasiewicz et al. (2025) studied this question.

synapsesocial.com/papers/69401d682d562116f28f9120https://doi.org/10.3390/nu17243843
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Body Composition by Bioelectrical Impedance Analysis: Associations with Nutritional Status, Functional Limitations, and Chronic Diseases in Older Adults2026 · 2 citations
  2. 2Associations of Bioelectrical Impedance-Derived Phase Angle and Hydration Parameters with Clinical Severity in Ambulatory Chronic Heart Failure2026
  3. 3Analyzing the correlation between body composition variables and cellular phase angle via computerized bioelectrical impedance analysis (BIA)2024
  4. 4Role of Bioelectrical Impedance Analysis in Detecting Nutritional Disorders in Institutionalized Psychogeriatric Patients2025
  5. 5Elevated extracellular water to total body water ratio and low phase angle in relation to muscle function in middle-aged and older adults2025 · 12 citations