Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 9, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

Combined bone marrow mesenchymal stem cell-derived nanovesicles and low-level laser therapy potentiate proliferation and osteogenesis of bone marrow mesenchymal stem cells

View Full Paper
Ask AI
Bookmark
Share

Authors

JZJingwei ZhangTYTonghao YaoQHQi Han

Discussion

Loading...

Member takes

Overview

Combined treatment improves osteogenesis in bone marrow mesenchymal stem cells, suggesting a novel bioengineering approach.

Key Points

  • This research aims to enhance the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells via two innovative techniques.
  • Cell proliferation measured with CCK-8 assay
  • Osteogenic differentiation assessed through alkaline phosphatase staining and alizarin red staining
  • Real-time quantitative PCR used to evaluate osteogenic gene expression
  • Combined treatment increased BMSC proliferation capacity compared to individual treatments
  • Enhanced alkaline phosphatase activity and mineralized nodule formation
  • Upregulation of key osteogenic genes, including ALP and RUNX2, was observed

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/69401d682d562116f28f91cahttps://doi.org/10.3389/fbioe.2025.1676777
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Combined Light and Thermal Stimulation of Bone Marrow Stem Cells2024 · 4 citations
  2. 2Bone Regeneration of Rat Critical-Sized Calvarial Defects by the Combination of Photobiomodulation and Adipose-Derived Mesenchymal Stem Cells2024 · 7 citations
  3. 3Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration2026 · 2 citations
  4. 4Ultrasound‐Mediated Biotransfection of Engineered Bone Marrow Mesenchymal Stem Cells in Treated Bone Defects through Intracellular Cavitation2025 · 4 citations
  5. 5Potentials of BMSCs for regulating osteogenic–vascular–neural–lymphatic coupling in bone regeneration2026