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Case report details chondroblastic osteosarcoma in a 33-year-old woman, suggesting factors affecting prognosis and potential treatment options.
Osteosarcoma is a malignancy of mesenchymal cells that have the ability to produce osteoid or immature bone. Chondroblastic osteosarcoma as constitute a substantial proportion of all osteosarcomas of the jaws. Some examples may be composed almost entirely of malignant cartilage growing in lobules with only small foci of direct osteoid production by tumor cells being identified. Chondroblastic osteosarcoma is a rare and aggressive type of bone cancer that tends to occur in the long bones of the arms and legs, although it can happen in any bone in the body. The cause of chondroblastic osteosarcoma is unknown, but it has been linked to specific genetic mutations and environmental factors. It is most common in adolescents and young adults and is characterized by malignant cartilage-forming cells. The prognosis for chondroblastic osteosarcoma depends on several factors, including the size of the tumor and its location, how far it has spread, and the patient's age and general health. Treatment typically involves a combination of surgery, chemotherapy, and radiation. Here, we present a rare case of maxillary chondroblastic sarcoma in a 33-year old woman presenting with a mass in the right quadrant of the maxilla. The lesion is sized as 42*25*30mm and is expanded from the lateral incisor tooth region area to the tuberosity in the anteroposterior dimension, from the alveolar crest to the maxillary sinus.
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Mostafazadeh et al. (2025) studied this question.
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