December 8, 2025Blood AdvancesOpen Access

Evaluating the American Society of Hematology Quality Measure on Timeliness of Analgesics for Sickle Cell Disease Pain Crisis

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Analysis shows poor performance in pain medication timeliness for sickle cell disease, indicating need for improvements.

Pain medication timeliness averaged 81 to 82.5 minutes across the study, with many sites exceeding 60 minutes.
Study used electronic health records data comprising 474,409 SCD VOE encounters from 225 sites visited between 2019 and 2024.
Pediatric sites had median times for pain medication 25 minutes lower than adult sites, suggesting performance disparities across age groups.
The overall performance of sites was notably poor on the quality measure, highlighting urgent needs for improvement.

Gwarzo et al. (2025) studied this question.

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