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September 5, 2025JAMA PediatricsOpen Access

Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain

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Authors

IGIbrahim GwarzoThomas Jefferson UniversityKCKeli D. ColemanChildren's Hospital of WisconsinKMKenneth McKinleyChildren's National

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Overview

Cross-sectional study shows timely opioid delivery lowers hospitalization rates in children with acute sickle cell pain, highlighting the importance of initial pain management.

Key Points

  • Timely administration of opioids in the ED reduces hospitalizations for acute sickle cell pain.
  • First-dose administration within 60 minutes is linked to a 16% reduction in hospitalization.
  • Combining first and second-dose timeliness minimizes hospitalizations, especially with first doses given in under 60 minutes.
  • Longer intervals between doses still correlated with lower hospitalization rates, emphasizing the need for timely pain management.

Cite This Study

Gwarzo et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f586d6d5674bcd0378ehttps://doi.org/10.1001/jamapediatrics.2025.2967
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Also Consider

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