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December 8, 2025Knee Surgery Sports Traumatology ArthroscopyOpen Access

Periprosthetic joint infection risk is comparable between unicompartmental knee arthroplasty to total knee arthroplasty conversion and primary total knee arthroplasty: A systematic review and meta‐analysis

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Authors

MDMatthew T. DeRuyterZLZachary C. LumJSJürgen Slapar

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Overview

Systematic review and meta-analysis reveal similar periprosthetic joint infection rates between unicompartmental to total knee arthroplasty conversion and primary total knee arthroplasty.

Key Points

  • No significant difference in periprosthetic joint infection rates was found between unicompartmental knee arthroplasty conversion and primary total knee arthroplasty.
  • The study reviewed data from six retrospective studies, involving 456 conversion cases and 719 primary total knee arthroplasties.
  • The method used for the analysis was a systematic review and random-effects meta-analysis of clinical studies.
  • Findings indicate the surgical complexity of unicompartmental to total knee arthroplasty conversion may require more revision-specific components.

Cite This Study

DeRuyter et al. (2025) studied this question.

synapsesocial.com/papers/694020e22d562116f28fa971https://doi.org/10.1002/ksa.70228
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Conversion Unicompartmental Knee Arthroplasties to Primary and Revision Total Knee Arthroplasties: A Gradient of Complexity2026
  2. 2Data from the Swiss National Arthroplasty Registry SIRIS suggest that unicompartmental knee arthroplasty is associated with a lower risk of periprosthetic joint infection than total knee arthroplasty.2026
  3. 3Data from the Swiss National Arthroplasty Registry SIRIS suggest that unicompartmental knee arthroplasty is associated with a lower risk of periprosthetic joint infection than total knee arthroplasty2026
  4. 4Conversion of UKA to TKA using identical standard implants—How does it compare to primary UKA, primary TKA and revision TKA?2024 · 4 citations
  5. 5Lower re‐revision rates after UKA‐to‐TKA than UKA‐to‐UKA revision for failed medial unicompartmental knee arthroplasty at mid‐term follow‐up2026