Key result
Abnormal or changing PR intervals are linked to increased risks of cardiac events and mortality.
Why the study?
Are the index-PR interval and its temporal changes associated with increased risk of cardiac events and all-cause mortality?
Population
2,234,492 patients with nationwide hospital ECGs linked with Danish national registries, 53% female…
Comparison
Index-PR interval and absolute temporal changes… vs Reference PR interval categories
Design
Cohort
Follow-up
median 7.1 years
Authors
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Both short and long PR intervals, as well as temporal changes in the PR interval, are associated with an increased risk of adverse cardiac events and all-cause mortality.
Cohort (n=2,234,492)
Yes
Are the index-PR interval and its temporal changes associated with increased risk of cardiac events and all-cause mortality?
Both short and long PR intervals, as well as temporal changes in the PR interval, are associated with an increased risk of adverse cardiac events and all-cause mortality.
Zheng et al. (2025) conducted a cohort in Cardiac events and mortality (n=2,234,492). PR interval and temporal changes (ΔPR) vs. Normal PR interval was evaluated on Cardiac events (atrial fibrillation/flutter, heart failure, ventricular arrhythmias, syncope, high-degree AV block) and all-cause mortality. Abnormal index PR intervals (short or long) and temporal PR changes were associated with increased risks of atrial fibrillation, heart failure, ventricular arrhythmias, and mortality (P<0.05).
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