Key result
In patients with coronary heart disease, a decreasing PR-interval below 162 ms was associated with increased all-cause mortality (HR 1.057 per 10 ms decrement; 95% CI 1.019-1.096; P=0.0030).
Why the study?
Is PR-interval duration associated with major cardiovascular outcomes in patients with coronary heart disease?
Population
9,637 patients with known coronary heart disease in sinus rhythm undergoing coronary angiography, median age…
Comparison
Shorter PR-interval (<162 ms) vs Longer PR-interval (>162 ms)
Design
Cohort
Authors
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Should not yet change risk assessment in coronary disease; leaves open whether short PR-interval adds prognostic value beyond existing models.
Cohort (n=9,637)
No
Is PR-interval duration associated with major cardiovascular outcomes in patients with coronary heart disease?
Hazard Ratio: 1.057 (95% CI 1.019–1.096)
p-value: p=0.0030
In patients with coronary heart disease, a shorter than normal PR-interval (<162 ms) is independently associated with increased all-cause mortality and major cardiovascular events.
Holmqvist et al. (2014) conducted a cohort in coronary heart disease (n=9,637). Decreasing PR-interval (<162 ms) vs. PR-interval >162 ms was evaluated on all-cause mortality (HR 1.057, 95% CI 1.019-1.096, p=0.0030). In patients with coronary heart disease, a decreasing PR-interval below 162 ms was associated with increased all-cause mortality (HR 1.057 per 10 ms decrement; 95% CI 1.019-1.096; P=0.0030).
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