Observational analysis revealed gut microbiota alterations linked to metabolic pathways in type 1 diabetes, suggesting new intervention strategies.
Our study reveals profound structural and functional alterations in the gut microbiome of individuals with T1D. These findings support the existence of a gut microbial-metabolite axis in autoimmune diabetes and suggest that microbial biomarkers and metabolic pathways may serve as novel targets for early diagnosis and therapeutic intervention. Longitudinal studies are warranted to validate these signatures and explore microbiota-based therapies for T1D prevention and management.
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Bima et al. (2025) studied this question.
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