December 6, 2025BMC GenomicsOpen Access

Plate-based 10X Genomics-compatible single-cell RNA-sequencing based on Smart-seq3xpress

View Full Paper

Ask AI

Bookmark

Authors

Discussion

New method demonstrates improved gene expression profiling in single-cell RNA-sequencing, suggesting innovative applications in transcriptomics.

PB10X enables effective gene expression analysis in limited cell populations with single-cell RNA-sequencing.
The method maximized performance in profiling, achieving 81.71% paired TCRαβ chains and mapped reads.
Assessment involved generating sequencing libraries from Jurkat lymphoblasts alongside 10X comparisons.
This advancement highlights the significance of microfluidics integration for cost-effective transcriptomics applications.

Deserranno et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

New method demonstrates improved gene expression profiling in single-cell RNA-sequencing, suggesting innovative applications in transcriptomics.