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December 6, 2025Molecular CancerOpen Access

Extracellular vesicles cargo orchestration in colorectal cancer: immune evasion, stromal remodeling, and therapeutic frontiers

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Authors

XLXiulan LiuKunming University of Science and TechnologyTZTingting ZhangWannan Medical CollegeMLMeijin LiuGanzhou People's Hospital

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Overview

This review discusses extracellular vesicles' roles in colorectal cancer and their potential as biomarkers, indicating new therapeutic strategies.

Key Points

  • Colorectal cancer development is influenced by the roles of extracellular vesicles in the tumor microenvironment, highlighting immune evasion mechanisms.
  • Biomarker potential of extracellular vesicles may assist in the early diagnosis and metastasis prediction of colorectal cancer cases.
  • Adjuvant immunotherapy is one of several therapeutic strategies using extracellular vesicles to treat colorectal cancer effectively.
  • The review identifies limitations in extracellular vesicle research while emphasizing future prospects for precise colorectal cancer diagnosis and treatment.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/694020fd2d562116f28fb6b3https://doi.org/10.1186/s12943-025-02532-2
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