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December 5, 2025Hematology

Buckle up! Managing surgery in patients with bleeding disorder of unknown cause

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Authors

CBCallie Berkowitz

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Overview

Observational analysis of bleeding risks in patients with BDUC, suggesting antifibrinolytic therapies may reduce postoperative complications.

Key Points

  • Antifibrinolytic agents may help manage bleeding in patients with BDUC, leading to improved surgical outcomes.
  • Key therapies include tranexamic acid and desmopressin to address hemostatic deficiencies.
  • Observational analysis across patients with negative hemostatic evaluations reveals complexities in management.
  • Multisite clinical trials may be needed to understand better the hemostatic strategies for BDUC.

Cite This Study

Callie Berkowitz (2025) studied this question.

synapsesocial.com/papers/6940224e2d562116f28fc105https://doi.org/10.1182/hematology.2025000694
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Also Consider

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  1. 1How to treat patients with bleeding disorder of unknown cause?2024 · 5 citations
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  4. 4How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation2026
  5. 5Dental surgery for patients with bleeding disorder of unknown cause2025