December 5, 2025Advanced Healthcare MaterialsOpen Access

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

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Membrane vesicles from lacticaseibacillus casei BL23 elicit an immune response and inhibit growth of Escherichia coli.
Cytokine levels, including pro-inflammatory markers, increased in response to membrane vesicle treatment.
Isolation involves ultracentrifugation and size exclusion chromatography to obtain stable vesicles of around 178 nm.
These vesicles may combat infections and improve immune function, suggesting potential for addressing antibiotic resistance.

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Implication

Antimicrobial assays demonstrate that lacticaseibacillus casei BL23 membrane vesicles enhance immune response against Escherichia coli, indicating a novel approach to antibiotic resistance.

Cite This Study

Jahromi et al. (2025) studied this question.

synapsesocial.com/papers/694022612d562116f28fc836 https://doi.org/10.1002/adhm.202500548

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Implication

Antimicrobial assays demonstrate that lacticaseibacillus casei BL23 membrane vesicles enhance immune response against Escherichia coli, indicating a novel approach to antibiotic resistance.

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Key Points

Discussion

Implication

Cite This Study

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Key Points

Discussion

Implication

Cite This Study

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