Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 3, 2025

Design and bioinformatic characterization of multi-epitope candidate vaccine derived from structural protein of SARS-CoV-2 Alpha, Delta, and Omicron variants

View Full Paper
Ask AI
Bookmark
Share

Authors

DDiyantoroFRFedik Abdul RantamJJuniastuti

Discussion

Loading...

Member takes

Overview

Bioinformatic characterization reveals strong immune responses in multi-epitope vaccine against SARS-CoV-2 variants, indicating broad antigenicity and stability.

Key Points

  • The multi-epitope vaccine showed favorable antigenicity and solubility, confirming its potential effectiveness against SARS-CoV-2 variants.
  • Molecular docking revealed strong binding interactions with immune receptors, leading to robust immune response simulations.
  • In silico analyses assessed toxicity and other physicochemical parameters, enhancing vaccine safety for use.
  • Findings indicate the potential for long-term immune memory as demonstrated through humoral and cellular response simulations.

Cite This Study

Diyantoro et al. (2025) studied this question.

synapsesocial.com/papers/694025972d562116f28feccchttps://doi.org/10.1051/bioconf/202519803001/pdf
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In silico design and evaluation of a multi-epitope vaccine targeting SARS-CoV-2 structural proteins2026 · 2 citations
  2. 2Immunoinformatics design of a structural proteins driven multi-epitope candidate vaccine against different SARS-CoV-2 variants based on fynomer2024 · 51 citations
  3. 3Engineering receptor-binding domain and heptad repeat domains towards the development of multi-epitopes oral vaccines against SARS-CoV-2 variants2024 · 2 citations
  4. 4Novel Design for Multi-Epitope Vaccines of COVID-19 and Critical In-Silico Assessment Steps2024
  5. 5Vaccine Design from the Ensemble of Surface Glycoprotein Epitopes of SARS-CoV-2: An Immunoinformatics Approach2020 · 75 citations