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December 1, 2025HLA

Characterisation of the Novel HLA‐DQA1*03:02:05 Allele by Next‐Generation Sequencing

Qimin Wu Wei Zhang Faming Zhu

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Key Points

The result indicates the presence of a unique nucleotide substitution at position 639.
Findings show a key difference between HLA-DQA1*03:02:05 and HLA-DQA1*03:02:01:01 alleles.
Assessment using next-generation sequencing highlights the genetic variation in the studied alleles.
This may enable further research on allele diversity in diverse populations.

Implication

Analysis reveals a nucleotide substitution at position 639 in the HLA-DQA1*03:02:05 allele, suggesting genetic diversity.

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/69402a5e2d562116f2901879 https://doi.org/10.1111/tan.70478

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterisation of the Novel <i>HLA‐DQA1*05:65:01:01</i> Allele by Next‐Generation SequencingOriginal Research · 2026 · 2 citations
2Characterisation of the Novel <i>HLA‐DQA1*01:02:32</i> Allele Using Third‐Generation Sequencing MethodsOriginal Research · 2026 · 1 citations
3Characterisation of the Novel <i>HLA‐DQB1*03:03:37</i> Allele by Next Generation SequencingOriginal Research · 2026 · 2 citations
4Characterisation of the Novel <i>HLA‐DQB1*06:03:58</i> Allele by Next‐Generation SequencingOriginal Research · 2026 · 1 citations
5Characterisation of the Novel <i>HLA‐DQA1*04:01:13</i> Allele by Sequencing‐Based TypingOriginal Research · 2026 · 1 citations

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Characterisation of the Novel <i>HLA‐DQB1*03:609</i> Allele by Next Generation Sequencing2026

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