Characterisation of the Novel HLA‐DQA1*04:01:13 Allele by Sequencing‐Based Typing

Key Points

• To characterise the newly identified HLA-DQA1*04:01:13 allele in comparison to its close variant.
• Utilised sequencing-based typing methods to analyze alleles.
• Focused on nucleotide substitutions at specific codons.
• Examined exon 3 for detailed genetic differences.
• Identified one nucleotide substitution at codon 90 compared to HLA-DQA1*04:01:01:03.
• Confirmed the uniqueness of the HLA-DQA1*04:01:13 allele.