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December 1, 2025Age and AgeingOpen Access

Anticholinergic Burden Recognition and Management in Older Hospitalised Patients

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Authors

DODenis O’MahonyUniversity College Cork

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Implication

Prospective study shows high anticholinergic burden and associated risks in hospitalized elderly patients, suggesting improved medication review is needed.

Key Points

  • Higher anticholinergic burden scores on admission and discharge indicate significant risks for older patients, especially with dementia.
  • 41.3% of patients had moderate-to-high anticholinergic burden initially, which increased to 43.4% at discharge.
  • Assessment using multiple anticholinergic burden scales demonstrated a strong link between increased scores and polypharmacy.
  • Increased awareness of anticholinergic drugs is essential for better management of cognitive and functional health.

Cite This Study

Denis O’Mahony (2025) studied this question.

synapsesocial.com/papers/69402a652d562116f290197bhttps://doi.org/10.1093/ageing/afaf318.112
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anticholinergic Burden at Admission and Discharge Among Geriatric Inpatients: A Single-Center Retrospective Cohort Study2026
  2. 2Anticholinergic burden and clinical outcomes among older adults admitted in a tertiary hospital: a prospective cohort study2025 · 3 citations
  3. 3Staff Awareness of Anti-Cholinergic Burden (ACB) - A Qualitative Cross-Sectional Study in a Tertiary Care Hospital2021 · 9 citations
  4. 42336 Prevalence of anticholinergic burden across a cohort of frail older adults in a district general Hospital in South West Wales2024 · 1 citations
  5. 5Anticholinergic Burden of Geriatric Ward Inpatients2021 · 8 citations