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October 16, 2021MedicinaOpen Access

40.73% of patients had at least one anticholinergic drug, and an ACB score ≥ 1 was significantly associated with dementia and risk of falls.

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Why the study?

Anticholinergic drug use in older adults is common despite an increased risk of side effects, prompting evaluation of its prevalence and total burden in hospitalized geriatric patients.

Is anticholinergic drug burden associated with dementia, risk of falls, and severe disability in geriatric ward inpatients?

Population

329 subjects hospitalized at an acute care geriatric ward in Poland

Comparison

Anticholinergic drug burden assessed by the Anticholinergic Cognitive Burden scale

Design

Cross-sectional study

Authors

KWKrzysztof WilczyńskiMGMarta GorczycaJGJagna Gołębiowska

Discussion

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Member takes

Overview

May support ACB review in frail geriatric inpatients; leaves open whether reducing burden improves dementia, falls, or disability.

Structured PICO

Is anticholinergic drug burden associated with dementia, risk of falls, and severe disability in geriatric ward inpatients?

P
Population
329 subjects hospitalized at an acute care geriatric ward in Poland, mean age 79.61 ± 6.82 years.
I
Intervention
Anticholinergic drug use (assessed by Anticholinergic Cognitive Burden (ACB) scale)
O
Outcome
Prevalence of anticholinergic drug use and total anticholinergic drug burden, and associations with dementia, risk of falls, and severe disabilitysafety

Anticholinergic drug use is common among geriatric inpatients and is associated with an increased risk of dementia, falls, and severe disability.

Cite This Study

Wilczyński et al. (2021) studied this question.

synapsesocial.com/papers/6a80bb97416558f5ced47c06https://doi.org/10.3390/medicina57101115
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