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December 1, 2025Food Science & NutritionOpen Access

Comparative Study of Hypoglycemic Effects and Mechanisms of Crude and Wine‐Processed Polysaccharides From Polygonatum sibiricum

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Authors

HYHui YangHenan Academy of Agricultural Sciences SZShuhua ZhaoSecond Affiliated Hospital of Jilin University MLMichael Z. LiTongji University

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Implication

Comparative analysis reveals polysaccharides improve weight loss in T2DM rats, suggesting potential clinical applications for crude and processed variants.

Key Points

Weight loss resulted from polysaccharides treatment in a type 2 diabetes rat model, indicating efficacy.
Data showed significant reduction in glucose and markers of oxidative stress with both crude and wine-processed polysaccharides.
Evaluation involved employing streptozotocin-induced T2DM models and HepG2 cell lines to assess mechanisms.
Findings underscore the potential of polysaccharides from Polygonatum sibiricum as therapeutic food candidates.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/69402a862d562116f29024c3 https://doi.org/10.1002/fsn3.71216

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Implication

Comparative analysis reveals polysaccharides improve weight loss in T2DM rats, suggesting potential clinical applications for crude and processed variants.

Comparative Study of Hypoglycemic Effects and Mechanisms of Crude and Wine‐Processed Polysaccharides From Polygonatum sibiricum

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparative Study of Hypoglycemic Effects and Mechanisms of Crude and Wine‐Processed Polysaccharides From Polygonatum sibiricum

Discussion

Member takes

Implication

Key Points

Cite This Study

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