Salivary Gland Choristoma at the Esophagogastric Junction Associated With Chronic Gastroesophageal Reflux Disease

Salivary gland choristoma at the esophagogastric junction (EGJ) is a rare benign lesion, typically presenting as a nodule. Though heterotopic salivary tissue can appear in the head, neck, or GI tract, its occurrence at the EGJ is uncommon. It is often discovered incidentally during endoscopy for chronic GERD. The origin remains unclear, with theories including embryologic misplacement, inflammation-induced differentiation, or proliferation of native glandular cells. We report two cases of EGJ choristomas in patients with Barrett's esophagus and chronic GERD. We aim to emphasize the importance of recognizing choristoma as a potential differential diagnosis when encountering a new nodule.