Multi-target mechanisms of Bojungikki-tang in psoriasis-like dermatitis: Integrative network and transcriptomic analysis

This study demonstrated that BJT ameliorated psoriasis-like inflammation by concurrently regulating pivotal pro-inflammatory cytokines and two distinct steps of the AA pathway, which may be related to its multi-component composition. These findings indicate the therapeutic potential of the multi-component drug BJT on multiple targets for psoriasis-like inflammation.