What question did this study set out to answer?

To compare rates of sars-cov-2 breakthrough infection in vaccinated individuals with and without HIV.

January 6, 2026AIDS0 citations

SARS-CoV-2 breakthrough infection among people with and without HIV in Ontario, Canada

CFCassandra Freitas CCC L CooperOttawa Hospital AKAbigail E. Kroch3M (United States)

Key Points

To compare rates of sars-cov-2 breakthrough infection in vaccinated individuals with and without HIV.
Population-based cohort study
Matched cohorts of people with and without HIV
Analysis included sociodemographic factors and previous infections
Breakthrough infection risk was similar between cohorts after adjustments
Higher rates of breakthrough infection observed in men with HIV before the Omicron variant

Abstract

We found that risk of SARS-CoV-2 breakthrough infection did not meaningfully differ between a population-based cohort of vaccinated people with HIV and a matched cohort of people without HIV after accounting for sociodemographic factors, previous SARS-CoV-2 infection, SARS-CoV-2 testing patterns and COVID-19 vaccine doses (14 December 2020 to 5 May 2024). However, rates of breakthrough infection were higher among men with HIV compared to without HIV during the pre-Omicron era.

问 AI

Bookmark

View Full Paper