Study on the synthesis and biological activity of kojic acid–piperazine derivatives

Key Points

• The study aims to explore the synthesis and biological activity of kojic acid-piperazine derivatives as tyrosinase inhibitors.
• Synthesis of kojic acid-piperazine derivatives
• Evaluation of biological activity against tyrosinase
• Assessment of potential applications in pharmaceuticals and cosmetics
• Identified effectiveness of kojic acid-piperazine derivatives as tyrosinase inhibitors
• Demonstrated enhanced biological activity compared to traditional inhibitors
• Suggests utility in pharmaceutical and cosmetic formulations