The Relation between Ambient Temperature and Asthma Exacerbation in Children: A Systematic Review

Background: Asthma is one of the most common chronic noncommunicable diseases which is seen more in the developed than developing countries of the world.Recurrence and exacerbations of the disease are common among patients and often lead to hospitalization and therapeutic interventions.Ambient air temperature might be related to the relapse of asthma.This review was conducted to investigate the relation between ambient temperature and exacerbations of asthma in children.Methods: Related articles were searched in PubMed, Web of Science, Science Direct, and Scopus databases with appropriate keywords and no specific limitation on October 1, 2018.Initially, the relevance of the articles was examined using the title and abstract.Out of 2633 articles, 23 articles were eligible according to the inclusion and exclusion criteria.Results: Fourteen studies had reported inverse relations; and showed as the temperature dropped, the number of asthma attacks increased in children.Nine papers observed a relation between hot weather and asthma attacks, 3 studies reported a relation between temperature differences and asthma attacks, and two studies did not show any relation.Some studies suggested the increased incidence of asthma in the 5-14 year old age group was associated with the start of the school year and probably due to the spread of viral diseases, not temperature changes. Conclusion:Extreme temperatures are likely to cause exacerbation of childhood asthma.