What question did this study set out to answer?

To describe the infrastructure improvements, analytical updates, and new public resources developed for the PRIDE proteomics repository since 2019.

October 16, 2021Nucleic Acids ResearchOpen Access

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

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To describe the infrastructure improvements, analytical updates, and new public resources developed for the PRIDE proteomics repository since 2019.
Upgraded PRIDE Archive pipelines to process expanding submissions of mass spectrometry-based proteomics data.
Developed the MAGE-TAB format tailored for proteomics to standardize and improve sample metadata annotation.
Integrated Universal Spectrum Identifiers for direct spectral querying and created aggregated peptide and protein evidence access through PRIDE Peptidome.
Submission volume into PRIDE Archive reached an average of approximately 500 datasets per month during 2021.
Deployed the PRIDE Spectra Archive to deliver direct mass spectral access alongside cross-dataset peptide identification via PRIDE Peptidome.
Expanded automated data dissemination pipelines to supply high-quality proteomics evidence to downstream resources including UniProt, Ensembl, and Expression Atlas.

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Implication

Database report demonstrates enhanced mass spectrometry data access and annotation in proteomics repositories, suggesting improved data reuse across global scientific databases.

Cite This Study

Pérez‐Riverol et al. (2021) studied this question.

synapsesocial.com/papers/696015f22a54df443d888eee https://doi.org/10.1093/nar/gkab1038

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Implication

Database report demonstrates enhanced mass spectrometry data access and annotation in proteomics repositories, suggesting improved data reuse across global scientific databases.

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Key Points

Discussion

Implication

Cite This Study

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Key Points

Discussion

Implication

Cite This Study

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