Key result
Pravastatin reduced the incidence of all-cause stroke by 32% and stroke or TIA by 27% in patients after myocardial infarction compared to placebo.
Why the study?
Does pravastatin 40 mg/d reduce the incidence of stroke in patients with a prior myocardial infarction and average cholesterol levels?
Does pravastatin 40 mg/d reduce the incidence of stroke in patients with a prior myocardial infarction and average cholesterol levels?
Pravastatin 40 mg/d significantly reduces the incidence of stroke and TIA in post-myocardial infarction patients with average cholesterol levels, even with high concurrent antiplatelet use.
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Establishes statin therapy for secondary stroke prevention in post-MI patients with average.
Plehn et al. (1999) studied this question. Pravastatin reduced the incidence of all-cause stroke by 32% and stroke or TIA by 27% in patients after myocardial infarction compared to placebo.