Recurrent diffuse chorioamniotic hemosiderosis was observed in a mother with congenital heart disease, potentially linked to impaired uteroplacental perfusion from Fontan physiology.
Fontan physiology in mothers with congenital heart disease may contribute to impaired uteroplacental perfusion, increasing the risk for marginal hemorrhage and recurrent diffuse chorioamniotic hemosiderosis.
Absolute Event Rate: 0% vs 0%
A woman in her mid-20s with repaired congenital heart disease (CHD) delivered a 33-week neonate in 2024 following preterm labor and a 24-week neonate in 2025 for non-reassuring fetal heart tones. Placental examination in both cases revealed grossly abnormal, red-brown discolored membranes with a circumvallate insertion. Histologic evaluation demonstrated diffuse chorioamniotic hemosiderosis (DCH) in both cases. This report describes a novel case of recurrent DCH in a mother with CHD and proposes that Fontan physiology may contribute to impaired uteroplacental perfusion, increasing the risk for marginal hemorrhage.
Kim et al. (Mon,) reported a other. Recurrent diffuse chorioamniotic hemosiderosis was observed in a mother with congenital heart disease, potentially linked to impaired uteroplacental perfusion from Fontan physiology.
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