In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y

Juan M. Teran-Plasencia; André C. Kalil; ACP Journal Club Editorial Team at McMaster University

doi:10.7326/annals-25-04799-jc

January 5, 2026Annals of Internal Medicine

In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y

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Key result

Predischarge influenza vaccination linked to lower 1-year mortality or readmission in acute HF.

Why the study?

Does predischarge influenza vaccination reduce a composite of mortality or readmission at 1 year in adults hospitalized with acute heart failure?

Key Points

The aim is to assess the impact of predischarge influenza vaccination on mortality and readmission rates in adults with acute heart failure.
Evaluated adults hospitalized with acute heart failure
Administered influenza vaccination before discharge
Monitored mortality and readmission over one year
Influenza vaccination significantly reduced the composite of mortality or readmission rates
Patients who were vaccinated had better outcomes compared to those who were not
Findings suggest a potential benefit of vaccination in this at-risk population

Structured PICO

Does predischarge influenza vaccination reduce a composite of mortality or readmission at 1 year in adults hospitalized with acute heart failure?

P

Population

Adults hospitalized with acute heart failure

I

Intervention

Predischarge influenza vaccination

O

Outcome

Composite of mortality or readmission at 1 yearcomposite

Predischarge influenza vaccination reduces the composite of mortality or readmission at 1 year in adults hospitalized with acute heart failure.

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Implication

Supports predischarge vaccination in acute HF; hypothesis-generating and requires randomized confirmation.

Abstract

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Discussion

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Cite This Study

Teran-Plasencia et al. (2026) studied this question. Predischarge influenza vaccination reduced the composite rate of mortality or readmission at 1 year in adults hospitalized with acute heart failure.

synapsesocial.com/papers/696321d891e05aa366cb81ed https://doi.org/10.7326/annals-25-04799-jc

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In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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