Increased FUNDC2 expression in perivascular adipose tissue is linked to detrimental effects on mitochondrial dynamics and ferroptosis, contributing to hypertensive vascular remodeling.
FUNDC2 contributes to hypertensive vascular remodeling by regulating mitochondrial dynamics and ferroptosis in perivascular adipose tissue.
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Our findings indicated that increased FUNDC2 expression might lead to PVAT dysfunction and abnormal adipokine secretion, potentially through its link to mitochondrial dynamics and ferroptosis in PVAT adipocytes, therefore leading to hypertensive vascular remodeling.
Jin et al. (Thu,) reported a other. Increased FUNDC2 expression in perivascular adipose tissue is linked to detrimental effects on mitochondrial dynamics and ferroptosis, contributing to hypertensive vascular remodeling.
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