From Japan to the world; A new guidelines for hypertension managements from Japanese Society of Hypertension

Yusuke Ohya

doi:10.1038/s41440-025-02488-2

December 26, 2025Hypertension ResearchOpen Access

From Japan to the world; A new guidelines for hypertension managements from Japanese Society of Hypertension

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Key Points

To introduce the updated 2025 Japanese Society of Hypertension guidelines and provide practical, evidence-based recommendations for managing elevated blood pressure and hypertension in clinical practice.
Conducted systematic reviews and meta-analyses across 19 critical clinical questions to develop evidence-graded recommendations.
Performed structured evidence gathering and expert consensus syntheses for 11 additional frontline clinical questions.
Included multidisciplinary healthcare professionals, patient and public representatives, and applied strict conflict-of-interest eligibility criteria.
Hypertension is defined as office BP ≥ 140/90 mmHg, with normal blood pressure classified as < 120/80 mmHg.
A unified target BP of < 130/80 mmHg is established irrespective of age, comorbidities, or complications, with higher individualized targets reserved for frail older adults.
Lifestyle modifications maintain sodium restriction to < 6 g/day, introduce the urinary Na/K ratio as a biomarker, and advise resistance training in addition to aerobic exercise.

Structured PICO

P

Population

Patients with elevated blood pressure and hypertension, including specific guidance for older adults, pregnant women, and cancer patients.

I

Intervention

Management of elevated blood pressure and hypertension according to the JSH2025 guidelines, including a unified target BP of <130/80 mmHg, lifestyle modifications, and pharmacologic therapy.

Implication

The editorial highlights the key updates in the JSH2025 guidelines, notably the simplified, unified target blood pressure of <130/80 mmHg for most patients.

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Cite This Study

Yusuke Ohya (2025) studied this question.

synapsesocial.com/papers/6963221f91e05aa366cb8a08 https://doi.org/10.1038/s41440-025-02488-2

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From Japan to the world; A new guidelines for hypertension managements from Japanese Society of Hypertension

Key Points

Structured PICO

Implication

Discussion

Cite This Study

From Japan to the world; A new guidelines for hypertension managements from Japanese Society of Hypertension

Key Points

Structured PICO

Implication

Discussion

Cite This Study

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