Cardiomyocyte diameter decreased after aortic valve replacement, indicating regression of cellular hypertrophy without significant change in extracellular matrix volume.
Does aortic valve replacement reduce cellular hypertrophy and extracellular matrix volume in patients with severe aortic stenosis?
Aortic valve replacement in severe aortic stenosis leads to regression of cellular hypertrophy primarily through reduced cardiomyocyte diameter, without significant changes in extracellular matrix volume at 6 months.
Absolute Event Rate: 0% vs 0%
Cellular hypertrophy regressed 6 months following AVR; the extracellular matrix volume did not change significantly. τic decreased post-AVR, indicating that the reduction in cell volume can be largely attributed to a reduction in cardiomyocyte diameter.
Sharrack et al. (Thu,) reported a other. Cardiomyocyte diameter decreased after aortic valve replacement, indicating regression of cellular hypertrophy without significant change in extracellular matrix volume.