Purpose: To compare the predicted and actual corneal ablation depth in wavefront-guided laser in situ keratomileusis (WFG LASIK) and keratorefractive lenticule extraction (KLEx). Methods: This prospective, randomized, contralateral eye study included 26 patients 22 years or older with sphere between −0.75 to −8.00 diopters and 3.00 diopters of cylinder or less undergoing WFG LASIK and KLEx performed by a single surgeon at a large academic hospital. Actual ablation depth was calculated from preoperative and postoperative central corneal thickness. The iDesign aberrometer (Johnson 95% CI: 1.7 to 10.7; P = .02). Conclusions: Corneal ablations were deeper than predicted after WFG LASIK and shallower than predicted after KLEx. WFG LASIK was independently associated with greater ablation depth inaccuracy, but there was no difference in postoperative spherical equivalent between WFG LASIK and KLEx.
Ahluwalia et al. (Thu,) studied this question.