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January 14, 2026Journal of Clinical Oncology

Reevaluating complete response: Assessing whether imaging alone is sufficient to predict survival after transarterial radioembolization in hepatocellular carcinoma.

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Authors

DSDeepak SherpallyNew York Medical CollegeMMMina S. MakaryThe Ohio State UniversityKMKhalid MumtazThe Ohio State University Wexner Medical Center

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Implication

Retrospective review demonstrates imaging responses impact survival in HCC patients undergoing transarterial radioembolization, suggesting a need for improved surveillance strategies.

Key Points

  • This study aims to evaluate the prognostic value of post-TARE imaging responses in patients with hepatocellular carcinoma.
  • Conducted a single center retrospective review of HCC patients who underwent TARE from 2015 to 2022.
  • Evaluated clinical and pathological characteristics of patients and analyzed first post-TARE imaging responses.
  • Utilized Kaplan-Meier curves and log-rank tests to estimate overall survival and TARE-specific overall survival.
  • 126 of 141 patients met eligibility for evaluation.
  • Complete response on imaging did not guarantee superior survival without additional therapy.
  • Among imaging categories, partial response correlated with the best overall survival outcomes.

Cite This Study

Sherpally et al. (2026) studied this question.

synapsesocial.com/papers/6966f2fb13bf7a6f02c00679https://doi.org/10.1200/jco.2026.44.2_suppl.495
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Post-TARE Survival Outcomes in Hepatocellular Carcinoma: Influence of Pre-TARE Immunotherapy and Targeted Therapy in a Real-World Cohort2026
  2. 2Assessment of Preprocedural Factors Associated with 5-Year Complete Response After Transarterial Radioembolization in Patients with Hepatocellular Carcinoma2025
  3. 3Outcome of transarterial radioembolization in patients with hepatocellular carcinoma as a first-line interventional therapy and after a previous transarterial chemoembolization2024 · 5 citations
  4. 4Predictors of good outcomes in patients with hepatocellular carcinoma (HCC) treated with transarterial radioembolization (TARE).2024 · 1 citations
  5. 5Radiological Response and Characteristics of Patients Diagnosed With Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization: An Observational Study2025 · 1 citations