Key result
A tapered left ventricular outflow tract (LVOT) increased the rate of permanent pacemaker implantation after TAVI to 21% compared to 7% for non-tapered LVOT (p = 0.015).
Why the study?
Predicting the need for permanent pacemaker implantation after TAVI is crucial for procedural planning and patient counseling, prompting evaluation of whether LVOT morphology predicts post-TAVI conduction disturbances.
Does a tapered left ventricular outflow tract (LVOT) configuration predict the need for permanent pacemaker implantation in patients undergoing TAVI with the Evolut series?
Does a tapered left ventricular outflow tract (LVOT) configuration predict the need for permanent pacemaker implantation in patients undergoing TAVI with the Evolut series?
A tapered LVOT configuration, pre-existing RBBB, and deep valve implantation with a short membranous septum are strong independent predictors of needing a permanent pacemaker after TAVI with the Evolut platform.
Tapered LVOT was associated with higher PPM rates after Evolut TAVI; hypothesis-generating for morphology-based risk stratification pending prospective validation.
Background Predicting the need for permanent pacemaker implantation (PPM) after transcatheter aortic valve implantation (TAVI) is crucial for procedural planning and patient counseling. Aims To evaluate whether left ventricular outflow tract (LVOT) morphology, specifically a tapered configuration, predicts conduction disturbances requiring PPM after TAVI using the Evolut self‐expanding valve. Methods This retrospective multicenter study included patients undergoing TAVI with the self‐expanding Evolut series. Pre‐TAVI MSCT analysis included LVOT shape, membranous septum (MSep) length, and landing‐zone calcification. Implantation depth (ID) was measured on final aortography. Results A total of 189 patients were included (age, 79.2 ± 6.8 years, 46% female, EuroSCORE II, 3.1 [1.9, 5.6]). Seventeen patients (9%) required PPM at 30 days. Patients with a tapered LVOT had a threefold higher PPM rate compared with those with a non‐tapered configuration (21% vs. 7%, p = 0.015). PPM was significantly associated with tapered LVOT (OR: 4.2, p = 0.041), pre‐existing right bundle branch block (RBBB) (OR: 12.4, p = 0.001), and deep valve implantation with a short MSep (OR: 16.4, p < 0.001). Conclusion Tapered LVOT configuration, pre‐existing RBBB, and deep implantation in the context of a short MSep are independent predictors of PPM following TAVI with the Evolut TAVI platform. Integrating LVOT configuration and MSep length into preprocedural planning may improve patient selection and prediction of PPM.
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Abdelshafy et al. (2026) studied this question. A tapered left ventricular outflow tract (LVOT) increased the rate of permanent pacemaker implantation after TAVI to 21% compared to 7% for non-tapered LVOT (p = 0.015).
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