This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary objectives To evaluate the benefits and harms of physiology-guided PCI compared to angiography-guided PCI for cardiovascular events in individuals with CCS and ACS. Secondary objectives To assess potential differences in the effectiveness and safety of physiology-guided PCI according to patient characteristics, including sex and age, from the perspective of equity.
Higuchi et al. (Mon,) studied this question.