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April 24, 2024Journal of Clinical MedicineOpen Access

Comparison between Imaging and Physiology in Guiding Coronary Revascularization: A Meta-Analysis

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Why the study?

The optimal choice between imaging-guided and physiology-guided PCI has been a subject of ongoing debate.

Does imaging-guided PCI reduce adverse cardiovascular events compared to physiology-guided PCI in patients with coronary artery disease?

Comparison

Imaging-guided vs physiology-guided PCI

Design

Meta-analysis

Follow-up

Mean 2.1 years

Authors

RIRiccardo ImprotaGPGianluca Di PietroMGMichele Giansanti

Discussion

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Overview

Imaging guidance may reduce TVR versus physiology guidance for ICLs; supports RCTs to confirm and extend findings.

Structured PICO

Does imaging-guided PCI reduce adverse cardiovascular events compared to physiology-guided PCI in patients with coronary artery disease?

P
Population
5,701 patients with coronary artery disease undergoing percutaneous coronary intervention (PCI) or management of intermediate coronary lesions (ICLs) pooled from 7 studies.
I
Intervention
Imaging-guided percutaneous coronary intervention (PCI)
C
Comparator
Physiology-guided (functional-guided) percutaneous coronary intervention (PCI)
O
Outcome
Major adverse cardiovascular events (MACE) at mean 2.1 years follow-uphard clinical

Imaging-guided PCI may reduce the need for future target vessel revascularization compared to physiology-guided PCI, regardless of acute coronary syndrome presentation.

Cite This Study

Improta et al. (2024) studied this question.

synapsesocial.com/papers/6a764ce99af63782f5bcbc13https://doi.org/10.3390/jcm13092504
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fractional flow reserve use in coronary artery revascularization: A systematic review and meta-analysis2023 · 12 citations
  2. 2Intracoronary imaging in PCI for acute coronary syndrome: Insights from British Cardiovascular Intervention Society registry2023 · 16 citations
  3. 3Cost-Effectiveness of Intravascular Imaging-Guided Complex PCI: Prespecified Analysis of RENOVATE-COMPLEX-PCI Trial2024 · 18 citations
  4. 4Long-Term Cost-Effectiveness of Fractional Flow Reserve–Based Percutaneous Coronary Intervention in Stable and Unstable Angina2022 · 10 citations