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July 21, 2025Frontiers in Cardiovascular MedicineOpen Access

Comparison of intravascular imaging, physiological assessment and angiography for coronary revascularization in acute coronary syndrome: a systematic review and network meta-analysis

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Authors

XLXuan-Yan LiuBYBin-Hua YeXWXian-Dan Wu

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Overview

Network meta-analysis shows that intravascular imaging reduces major adverse cardiovascular events in acute coronary syndrome patients, implying a shift in PCI techniques.

Key Points

  • Intravascular imaging and physiological assessment are more effective in reducing major adverse cardiovascular events after PCI compared to angiography.
  • IVUS and FFR-guided PCI show lower risk ratios (RR: 0.62) for MACE versus traditional angiography techniques.
  • The analysis included 28 randomized control trials involving over 18,000 patients to evaluate PCI outcomes.
  • Significant reductions in all-cause mortality were observed with QFR-guided PCI compared to angiography, highlighting its potential benefits.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd205https://doi.org/10.3389/fcvm.2025.1604050
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Intravascular Imaging–, Physiology‐, or Angiography‐Guided Approaches for Percutaneous Coronary Intervention: A Systematic Review and Network Meta‐Analysis2026 · 2 citations
  2. 2Contemporary evidence for intravascular imaging-guided percutaneous coronary intervention: a systematic review and meta-analysis of 21 812 patients from 18 randomized controlled trials2026
  3. 3Impact of percutaneous coronary intervention with different guidance modalities in patients with coronary artery lesions: a network meta-analysis and systematic review2025 · 1 citations
  4. 4Assessment of Coronary Stenoses for Percutaneous Coronary Intervention: A Systematic Review and Network Meta-Analysis of Randomized Trials2024 · 4 citations
  5. 5Comparison between Imaging and Physiology in Guiding Coronary Revascularization: A Meta-Analysis2024 · 2 citations