Bayesian analysis integrates new trial information with existing knowledge to reduce uncertainty and generate direct probability statements about treatment hypotheses in cardiovascular medicine.
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Reinforces Class I CABG preference in diabetic multivessel disease; extends FREEDOM trial via Bayesian synthesis but leaves open prospective validation.
Bittl et al. (2017) studied this question. Bayesian analysis supports a Class I recommendation for bypass surgery over percutaneous coronary intervention in multivessel coronary disease in diabetic patients.
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