Key result
Aortic valve area criteria classify more patients as having severe stenosis than mean pressure gradient or peak flow velocity, likely due to reduced stroke volume.
Why the study?
Does grading based on AVA compared to mean pressure gradient and peak flow velocity result in inconsistent classification of severe aortic stenosis in patients with normal systolic LV function?
Does grading based on AVA compared to mean pressure gradient and peak flow velocity result in inconsistent classification of severe aortic stenosis in patients with normal systolic LV function?
Echocardiographic criteria for severe aortic stenosis are inconsistent in patients with normal LV function, with AVA classifying more patients as severe compared to pressure gradients, potentially due to reduced stroke volume.
Answers are grounded in this paper and cite their sources.
May overclassify severe AS severity by AVA in preserved EF; leaves open need for refined, flow-adjusted criteria.
The criteria for the grading of aortic stenosis are inconsistent in patients with normal systolic LV function. On the basis of AVA, a higher proportion of patients is classified as having severe aortic valve stenosis compared with mean pressure gradient and peak flow velocity. Discrepant grading in these patients may be partly due to reduced stroke volume.
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Minners et al. (2007) studied this question. Aortic valve area criteria classify more patients as having severe stenosis than mean pressure gradient or peak flow velocity, likely due to reduced stroke volume.
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