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Novel method demonstrates high yield of rifamycin O from rifamycin B, implying efficient antibiotic synthesis.
A novel method of synthesizing the key antibiotic intermediate rifamycin O through the electrooxidation of rifamycin B (RB) was presented. Trace water addition enhanced the electrooxidation efficiency, achieving high yield and space–time yield.
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Liu et al. (2026) studied this question.
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