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To evaluate the diagnostic performance of 18F-FDG PET-CT in detecting cardiac inflammation in suspected cardiac sarcoidosis.

18F-fluorodeoxyglucose PET computed tomography in cardiac sarcoidosis: lessons from a 10-year review

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To evaluate the diagnostic performance of 18F-FDG PET-CT in detecting cardiac inflammation in suspected cardiac sarcoidosis.
Conducted a 10-year retrospective observational study at a teaching hospital.
Reviewed 397 18F-FDG PET-CT scans in 296 patients with suspected cardiac sarcoidosis.
Assessed diagnostic quality, patterns of FDG uptake, and concordance with cardiac MRI and myocardial perfusion imaging.
Achieved excellent diagnostic quality in 365 out of 397 scans (91.9%).
Identified cardiac inflammation in 226 patients and found normal scans in 139 patients.
Detected extracardiac sarcoidosis in 230 patients (63%).
Observed concordance of PET findings with MPI in 53% of cases, and high concordance with CMR in 85.7% (P < 0.001).
Follow-up PET-CT successfully monitored treatment in 66 out of 70 patients (94.2%).

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Observational review assesses diagnostic utility of 18F-FDG PET-CT in cardiac sarcoidosis, suggesting high concordance with MRI.

Pant et al. (2026) studied this question.

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