Key result
The index of microcirculatory resistance (IMR) increased significantly from 16.9±6.5 U to 25.9±14.4 U after disruption of the microcirculation (P =0.002).
Why the study?
Does the index of microcirculatory resistance (IMR) correlate with true microcirculatory resistance (TMR) in a swine model?
Population
9 Yorkshire swine in an open-chest model
Comparison
Index of microcirculatory resistance derived… vs True microcirculatory resistance derived from an…
Design
Preclinical
Authors
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IMR detects microcirculatory changes in swine; leaves open human validation before clinical adoption.
Does the index of microcirculatory resistance (IMR) correlate with true microcirculatory resistance (TMR) in a swine model?
IMR is a novel, simple, and quantitative invasive index that accurately assesses coronary microcirculatory resistance independent of epicardial stenosis in a preclinical model.
Fearon et al. (2003) studied this question. The index of microcirculatory resistance (IMR) increased significantly from 16.9±6.5 U to 25.9±14.4 U after disruption of the microcirculation (P =0.002).
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