What question did this study set out to answer?

The aim is to create and evaluate nanoparticles for delivering fenticonazole effectively to treat vaginitis.

January 18, 2026RSC Pharmaceutics0 citationsOpen Access

Development and Evaluation of Fenticonazole Nitrate Loaded Fucoidan Crafted Lecithin Chitosan Nanoparticles for the Treatment of Vaginitis

BVBhavana ValamlaNational Institute of Pharmaceutical Education and Research PCPadakanti Sandeep CharyNational Institute of Pharmaceutical Education and Research UAUrati AnuradhaNational Institute of Pharmaceutical Education and Research

Key Points

The aim is to create and evaluate nanoparticles for delivering fenticonazole effectively to treat vaginitis.
Developed fenticonazole loaded lecithin chitosan nanoparticles (FZNP).
Coated nanoparticles with fucoidan using ionic gelation method.
Assessed cationic zeta potential alterations in the formulation.
Successful creation of fucoidan coated nanoparticles (Fu-FZNP).
Altered physicochemical properties observed due to fucoidan coating.
Enhanced potential for targeted treatment of vaginitis.

Abstract

In this investigation, self-assembling nanoparticles Fenticonazole loaded lecithin chitosan nanoparticles (FZNP) with cationic zeta potential was altered by coating them with anionic fucoidan polymer (Fu-FZNP) through ionic gelation method to...

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