Prompt management with antipyretic treatment and implantable cardioverter-defibrillator improved outcomes in a patient with fever-induced Brugada syndrome and ST-segment elevation.
Highlights the importance of maintaining a high index of suspicion for Brugada syndrome in febrile patients presenting with ST-segment elevation and syncope, even in trauma settings.
We present the case of a woman in her mid-50s with suspected arrhythmic syncope while she was driving owing to fever-induced Brugada syndrome. The patient was appropriately managed with prompt antipyretic treatment and an implantable cardioverter-defibrillator. Clinicians should maintain a high index of suspicion for Brugada syndrome in febrile patients presenting with ST-segment elevation and syncope, even in trauma settings. Prompt electrocardiographic monitoring, antipyretic therapy and consideration of implantable cardioverter-defibrillator implantation are crucial in management.
Andreou et al. (2026) studied this question. Prompt management with antipyretic treatment and implantable cardioverter-defibrillator improved outcomes in a patient with fever-induced Brugada syndrome and ST-segment elevation.