What question did this study set out to answer?

This research aims to identify the optimal flushing volume for maintaining efficacy in power-injectable catheters post-iodinated contrast injection.

Flushing efficacy of high concentration iodinated contrast agent in power-injectable peripherally inserted central catheters: Evaluating different flush volumes in vitro

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Empirical in vitro experiment assesses flushing volumes for central catheters, suggesting optimal volumes for efficacy.

This research aims to identify the optimal flushing volume for maintaining efficacy in power-injectable catheters post-iodinated contrast injection.
Conducted an in vitro experiment with single lumen power-injectable catheters filled with iodinated contrast agent.
Randomized 60 catheters into four groups with flushing volumes of 10 ml, 15 ml, 20 ml, and 25 ml saline solution.
Applied a consistent pulsatile flushing technique across all groups.
Measured iodine recovery from the catheters' lumen.
Average iodine recovery was 98.5% in Group A (10 ml), 99.3% in Group B (15 ml), 98.4% in Group C (20 ml), and 97.2% in Group D (25 ml).
No significant differences in iodine recovery proportions between Group A and the other groups.
Concluded that 10 ml flushing volume is sufficient, as higher volumes do not improve efficacy and may add unnecessary fluid burden.

Guo et al. (2026) studied this question.

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