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The study assesses the efficacy of EUS-guided bilateral stent-in-stent deployment in patients with unresectable malignant hilar biliary obstruction.

Endoscopic Ultrasound‐Guided Bilateral Stent‐in‐Stent Deployment With Hepaticoenterostomy in patients With Malignant Hilar Biliary Obstruction

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The study assesses the efficacy of EUS-guided bilateral stent-in-stent deployment in patients with unresectable malignant hilar biliary obstruction.
Conducted a retrospective analysis of 20 patients with malignant hilar biliary obstruction after ERCP difficulties.
Applied EUS-guided stent-in-stent deployment for biliary drainage.
Evaluated technical and clinical success, adverse events, and recurrent biliary obstruction.
Achieved a technical success rate of 75% (15 out of 20 patients).
Clinical success observed in all technically successful cases.
Reported a 33% incidence of recurrent biliary obstruction requiring reintervention.
Early and late adverse event rates were 5% and 7%, respectively.
Median time to recurrent biliary obstruction was 161 days, with median overall survival at 191 days.

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This retrospective study examines EUS-guided stent deployment effectiveness in biliary obstruction, indicating its potential viability.

Inoue et al. (2026) studied this question.

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