Key result
Switching to e-cigarettes after PCI linked to ~18% lower MACE risk vs continued smoking.
Why the study?
Despite the increasing popularity of electronic cigarettes, the prognostic impact of switching to them in smokers with coronary artery disease after PCI remains unclear.
Does switching to electronic cigarettes or quitting smoking reduce major adverse cardiac events in smokers who underwent percutaneous coronary intervention compared to continued combustible cigarette use?
Population
17 973 adult smokers who underwent PCI in South Korea
Comparison
Switching to E-cigarettes vs quitting vs continuing combustible cigarettes
Design
Nationwide observational cohort study
Follow-up
Median 2.4 years
Authors
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Supports post-PCI cessation counseling; hypothesis-generating for e-cigarette switching and requires randomized confirmation.
Does switching to electronic cigarettes or quitting smoking reduce major adverse cardiac events in smokers who underwent percutaneous coronary intervention compared to continued combustible cigarette use?
Switching to electronic cigarettes or completely quitting smoking after PCI is associated with a significantly lower risk of major adverse cardiac events compared to continuing combustible cigarette use.
Kang et al. (2024) studied this question. Switching to E-cigarettes or quitting smoking after PCI was associated with lower MACE risk (HR 0.82 for switchers, HR 0.87 for quitters) compared to continued smoking.
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