Key result
Biventricular pacing prevented adverse left ventricular remodeling and reduction in ejection fraction compared to conventional right ventricular apical pacing in patients with normal systolic function
Why the study?
Does biventricular pacing prevent adverse left ventricular remodeling and reduction in left ventricular ejection fraction compared to right ventricular apical pacing in patients with bradycardia and normal ejection fraction?
Does biventricular pacing prevent adverse left ventricular remodeling and reduction in left ventricular ejection fraction compared to right ventricular apical pacing in patients with bradycardia and normal ejection fraction?
In patients with bradycardia and normal ejection fraction, biventricular pacing prevents the adverse left ventricular remodeling and decline in systolic function caused by conventional right ventricular apical pacing.
Supports biventricular over right ventricular apical pacing in bradycardia with preserved ejection fraction; strengthens low-certainty evidence from prior studies.
In patients with normal systolic function, conventional right ventricular apical pacing resulted in adverse left ventricular remodeling and in a reduction in the left ventricular ejection fraction; these effects were prevented by biventricular pacing. (Centre for Clinical Trials number, CUHK_CCT00037.)
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Yu et al. (2009) studied this question. Biventricular pacing prevented adverse left ventricular remodeling and reduction in ejection fraction compared to conventional right ventricular apical pacing in patients with normal systolic function.
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