Tandem electrophilic thiocyanation and cyclization yields thiocyanato isoxazoles, suggesting a new synthetic approach.
A tandem electrophilic thiocyanation/cyclization of 1,3-diphenyl-2-propyn-1-one O-methyloxime has been achieved under mild conditions. This method provides efficient access to a series of thiocyanato-containing isoxazole derivatives in moderate to excellent yields,...
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Liu et al. (2026) studied this question.
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